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Research indicates that roughly 50% of weight lost during semaglutide therapy returns within 12 years after stopping, though the exact amount varies based on diet, exercise, and genetic predisposition to weight regain

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Unfortunately, while antidiabetics and antihyperlipidemic help in CKD management, they are excreted by the kidneys and have a high risk of drug accumulation in renal cells which significantly contributes to CKD [221]

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Endocrine/metabolic Aug