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Emerging evidence suggests it may reduce inflammatory markers like high-sensitivity C-reactive protein (hsCRP), though whether this represents direct anti-inflammatory action or secondary benefits from metabolic improvements remains under investigation
doi: 10.3389/fnut.2025.1478542 Received 10 August 2024 Accepted 03 March 2025 Published 24 March 2025 Volume 12 - 2025 Edited by Jingjing Du, Max Planck Institute for Heart and Lung Research, Germany Reviewed by Qi Wang, Southern Medical University, China Silvio Pires Gomes, University of So Paulo, Brazil Updates Copyright 2025 Perumal, Arumugam, Osna, Rasineni and Kharbanda
The primary mechanism that promotes muscle catabolism is a calorie deficit, so counteracting those effects is the same
Sustainable Long-Term Use : Lower doses are often better tolerated long-term and may reduce cost if compounded formulations are used appropriately and legally
Lower back pain is not listed as a common or characteristic adverse effect in the FDA-approved prescribing information for semaglutide formulations (Ozempic, Wegovy, or Rybelsus)
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