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Moreover, since the inception of this study, multiple metabolic mechanisms promoting drug resistance have been suggested for 5FU treatment, including changes in amino acid metabolism 69,70 , serine and glycine metabolism 71,72,73 and glycolysis 74,75 , corroborated within our study and independently validating our findings

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doi:10.1038/nrn960 Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, Martins RN (2009) Cholesterol metabolism and transport in the pathogenesis of Alzheimers disease

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