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However, severe gastrointestinal side effectssuch as persistent vomiting or diarrhoeacan lead to dehydration, which may indirectly affect kidney function
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Concerns include lack of standardized quality oversight, salt forms that are not chemically identical to approved products, dosing errors from variable concentrations, counterfeit products, and increased adverse-event reporting signals
Based on observational data, a 2011 report highlighted an increased risk of pancreatitis and pancreatic cancer in patients using incretin therapy (Roshanov and Dennis, 2015)
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