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doi:10.1097/HJR.0b013e32828622d7 Sasaninia K, Kelley M, Abnousian A, et al

Jan 2021;56:102533

An oral dose of 1 to 5 mg will raise serum melatonin levels to 10 to 100 times the normal levels within an hour.[ref] Taking melatonin during the day increases daytime sleepiness and drops body temperature (something that normally happens around the time you go to bed at night).[ref] Melatonin is easily absorbed orally, subcutaneously, intranasally, transdermally, and sublingually

Understanding each phase helps patients and clinicians optimize therapeutic outcomes while managing side effects

veterans with type 2 diabetes to examine whether GLP-1 drugs influence addiction risk