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Nausea is the most common side effect, particularly during dose escalation

[1] Additionally, weight loss can temporarily affect energy levels as the body adapts to lower caloric intake

Carnitine deficiencies may cause symptoms such as fatigue, chest pain, muscle pain, weakness, low blood pressure, and/or confusion

The duration of the application varies depending on the area, but it is usually short and fast

For the two single-, double- and triple-composite endpoints in the PIONEER 3 trial, 2.7, 1.8, 2.6, and 2.1 patients needed to be treated with oral semaglutide 14 mg, respectively, and 7.3, 3.1, 10.4, and 5.0 patients needed to be treated with sitagliptin 100 mg, respectively, to bring one patient to target (Fig