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There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

A 2020 study found that those with vitamin B12 deficiency may present with cognitive disorder, though the deficiency was not shown to be a direct risk factor for cognitive decline ( However, results have been mixed and treatment with vitamin B12 wasnt effective at improving brain function in people with normal brain function ( Depression Its been suggested that there may be a link between low vitamin B12 levels and depression

Some people find that they prefer to have smaller quantities of B12 injected weekly or fortnightly, and others would rather take larger doses of B12 monthly

Two people researching the same compound are rarely candidates for the same approach, and the variables that matter are not visible in a search result