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Metal chaperones such as CQ and PBT2, which maintain metal ion homeostasis, have been shown to restore cognition, elevate zinc levels in the hippocampus, and restore levels of key proteins involved in learning/memory and synaptic plasticity in ZnT3 knockout mice
Antibiotic-mediated depletion of these protective species is the most common precipitant of Candida overgrowth
Wang L, Chen Y
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