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SIRT1 is NAD-dependent meaning it requires adequate NAD levels to function

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In terms of documented efficacy, this is not a close comparison: GLP-1 S has shown weight reductions in the range of 13-20% of body weight in clinical trials, while AOD-9604s pivotal trial failed to demonstrate a significant effect at that scale

GHK basic is the same tripeptide without the copper and demonstrates directly what the metal contributes, including the way an apo peptide scavenges copper from its surroundings