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Through this dual-receptor mechanism, tirzepatide exerts more potent actions on glycemic regulation, appetite suppression, and energy balance than conventional single-pathway GLP-1 receptor agonists
"Therapeutic potential of BPC-157 in nerve injury and repair." Peptides , 148, 170694.
Khan Z et al
Among them, tirzepatide is the most effective, with average weight loss of about 20% of body weight (Jastreboff AM et al, N Engl J Med 2022;387(3):205216)
Equally important to what you do during periods of weight loss is avoiding overly rapid loss of weight in the first place
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