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Animal models of colitis have demonstrated that GLP-1 receptor activation may reduce intestinal inflammation through multiple mechanisms, including modulation of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6), enhancement of intestinal barrier function, and reduction of oxidative stress
Handler P, Brabander D
It is mainly used for T2DM patients with sulfonylurea, metformin and their combination, which are difficult to control blood glucose
However, high dosage of APAP induces rapid necrosis of hepatic tissue, that could end up with ill-fated outcome and patients death
It plays a key role in protecting neurons from oxidative stress, supporting cognitive performance, and helping slow age-related cognitive decline
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