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5 Summary and outlook Heat stress-induced spermatogenic dysfunction in males is not caused by a single form of heat damage but rather results from the synergistic activity of multiple pathways, including protein homeostasis imbalance and oxidative stress accumulation, which collectively impair germ cells and disrupt spermatogenesis
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In addition to numerous prenylated proteins that contain the CAAX consensus, prenylation is known to occur on proteins of the RAB family of RAS-related G-proteins
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