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This explains why the plunger feels stuck or the needle appears cloggedthe medication itself has become unusable

Understanding these costs can help you make an informed decision about whether this treatment is right for you

In February 2026, full results from the REDEFINE 2 study showed CagriSema achieving 23% weight loss at 84 weeks but falling short of its primary endpoint under the treatment policy estimand (which measures efficacy across all patients regardless of whether they completed treatment, rather than only those who remained on it)

Patients must not self-medicate

see each drug's card for the per-product breakdown