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Its usually temporary and subsides after the vitamin is fully digested
In the blood, about 80% of cobalamin is bound to haptocorrin, forming holohaptocorrin, a complex that has a dual function: (1) holohaptocorrin conveys cobalamin to the liver, where it taken up through endocytosis (mediated by asialoglycoprotein receptor, ASGPR)
It simultaneously inhibits lipogenesis, the process of converting excess calories into new fat deposits
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However, deficiencies dont only have an effect on vegans and vegetarians
