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A sub-study of this trial focused on GC through the use of continuous glucose monitoring (CGM) and the proportion of time within a tight predefined time in range (TIR) from 71 to 140 mg/dL at the end of the study was considerably more significant in the group of participants receiving either 10 or 15 mg TZP competed to the group taking insulin degludec (72, 73, 75)

To check for B12 deficiency, doctors measure serum or plasma B12 levels

Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo

All three tirzepatide doses demonstrated superiority to semaglutide 1 mg for A1C reduction and non-inferiority was confirmed at every dose level

In Vitro 28, 240247 (2014)