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& Tsien, R
This study also confirmed the usefulness of the methionine-loading test to identify all of the subjects bearing an hyperhomocysteinemia-dependent cardiovascular risk
Dysregulated NLRP3 produces pro-inflammatory cytokines, IL-1 and IL-18, which serve to exacerbate myocardial damage initiating widespread inflammation within the cardiac tissue The activation of the NLRP3 inflammasome is related to several high-risk factors of DCM such as hyperlipidaemia, diabetes, obesity and hyperhomocysteinemia (100)
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They thank the personnel of the Teaching, Research, and Service Laboratories LADISER Clnicos and LADISER Inmunologa for allowing the use of their facilities to collect and analyze the biological samples
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