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Common gastrointestinal side effects including nausea, vomiting, and diarrhoea can reduce fluid intake and increase fluid losses, leading to dehydration and darker urine

If it occurs, these strategies help: Eat smaller, more frequent meals instead of large ones Avoid high-fat and greasy foods, which slow gastric emptying further Stay hydrated, dehydration worsens nausea significantly Ginger tea or ginger supplements have modest anti-nausea effects Consider timing your injection before bed so nausea peaks during sleep If nausea persists for more than three days after injection, or if it worsens with each dose, hold at your current dose for an additional one to two weeks before attempting an increase

[1] [3] It should be avoided in patients with Leber's hereditary optic neuropathy

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The study identified demographic-specific signals warranting clinical vigilance