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The latter cluster contained exclusively 5A-1MQ-treated animals switched from WD to LD (the WD/LD-T group), representing ~ 60% of all WD/LD-T animals

However, benefits depend on the specific peptide and the individuals overall health

In this Perspective article, we discuss how these critical challenges can affect our interpretation of research data in the field of obesity and the design and implementation of clinical guidelines

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