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Caroline Apovian, MD, Harvard Medical School The peptide appears to work through the beta-3 adrenergic receptor pathway, which is the same pathway activated during exercise-induced fat burning

A reduction in cravings and an increased sense of fullness after meals are common, leading to lower overall food consumption

The Medicines and Healthcare products Regulatory Agency (MHRA) approved tirzepatide following clinical trials demonstrating significant efficacy in HbA1c reduction and weight loss compared to placebo and some other diabetes treatments, including semaglutide 1 mg in the SURPASS-2 trial

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