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People who drank more coffee generally had lower levels of liver fat, iron, inflammation and fibrosis on imaging
202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione
Published rodent in vivo studies have used intraperitoneal injection and oral (gavage) administration
10.1002/gps.1469 Int
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