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& Momohara, S

A 2025 Japanese trial using 0.02% peptide lotion as standalone treatment observed a 7% increase in hair count after 16 weeks

3 mg dose = 0.06 mL (6 units)

GSTs catalyze the conjugation of acrolein to GSH and the corresponding conjugate is further modified by the enzymatic cleavage of the GSH glutamic acid and glycine residues by -glutamyltranspeptidase and cysteinylglycinase, respectively

This suppression is independent of plasma cholesterol changes and BW reduction through regulating markers of plaque instability and inflammation including those linked to plaque hemorrhage (CD163), matrix turnover (matrix metalloproteinase (MMP)-3, MMP-13), cholesterol metabolism (prostaglandin I2 synthase (PTGIS), ATP-binding cassette transporter 1 (ABCA1)), leukocyte recruitment (C-C motif chemokine ligand 2 (CCL2), osteopontin (OPN), interleukin (IL)-6), and leukocyte rolling, extravasation and adhesion (vascular cell adhesion molecule (VCAM)-1, E-selectin (SELE)) [16]