Briefly, mice were administered the GIPrAb (30 g/kg), fasted for 24 h, then linagliptin (10 mg/kg) or vehicle was administered prior to an oral glucose (2 g/kg) tolerance test
FEBS Lett 387:113116 Miao W, Jiang L, Xu F, Lyu J, Jiang X, He M, Liu Y, Yang T, Leak RK, Stetler RA, Chen J, Hu X (2021) Adiponectin ameliorates hypoperfusive cognitive deficits by boosting a neuroprotective microglial response
doi: 10.1007/s12602-022-09991-9 118 Lpez-MorenoA.SurezA.AvanziC.Monteoliva-SnchezM.AguileraM
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Human Equivalent Dose Calculations Using standard conversion formulas accounting for body surface area differences between species, a rat oral dose of 0.0045 mg/lb translates to approximately 0.00073 mg/lb in humans, yielding roughly 0.112 mg/day for a 154-pound person