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The intensity and duration of a reaction can vary

[15] Testosterone appears to be the primary androgen receptor-activating hormone in the Wolffian duct, whereas dihydrotestosterone is the main androgenic hormone in the urogenital sinus, urogenital tubercle, and hair follicles

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For multi-site or persistent cases: go with Glycopyrrolate 1% spray once daily

Methodological Confounds That Must Be Considered Before Comparing Cytokine Studies The biological mechanisms of cytokines make a consistent and stable circulating profile unlikely, which limits the ability of peripheral cytokines to provide insight into underlying pathophysiology in ME/CFS