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The progress varies depending on diet, activity level, and individual response to the medication
Toxicon 129, 5867
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Here's how small molecules built pharmaceutical empires: Lipitor (atorvastatin) Filed: 1985 | Launched: 1996 Peak sales: $12.9B annually Patent strategy: Multiple filings for different formulations Humira (adalimumab) Filed: 1999 | Launched: 2002 Revenue: $200B+ lifetime Patent wall: 130+ patents filed globally Nexium (esomeprazole) Filed: 1988 | Launched: 2001 Strategy: "Evergreening" from Prilosec Extended monopoly by 6+ years The pattern
Journal of Molecular Biochemistry, 7(2), 7884
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