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Other reports, in contrast, have suggested that hepatocytes lack functional GLP-1R, implying that the hepatic benefits of GLP-1 RAs may be mediated indirectly, for example through systemic metabolic improvements or modulation of the gut-liver axis
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Together, these findings indicate that heat-induced injury and subsequent recovery are clearly time-dependent
Some patients experience persistent gastrointestinal side effects that may limit long-term tolerability
Purging typically resolves within four to six weeks
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