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And I think that needs to be continued as we progress into using these medications for longer periods of time, to ensure that we know the entirety of the risks and the benefits of them

The combination of elevated insulin-like growth factor-1 and GH with increased glucose in the blood is a strong signal for the diagnosis of acromegaly

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Whatever the schedule, remodeling continues for weeks, so results are judged over a multi-week to multi-month horizon, not immediately