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These results suggest a potential benefit of LC supplementation in improving cardiovascular efficiency during the early stages of exercise

PMID: 41090431 | doi:10.1111/dom.70209 Katsi V et al

On the aversion side, GLP-1 receptors sit presynaptically on medial habenula terminals in the interpeduncular nucleus, where agonism potentiates glutamatergic input and brings forward nicotine's aversive properties