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Therapeutic advances in gastroenterology.Jul 2016;9(4):580-593

For those with malabsorption or neurological involvement, UK guidelines recommend hydroxocobalamin injections following specific loading and maintenance schedules

So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change

Insufficient hydration levels could impair metabolic processes and contribute to adverse reactions following the injection