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Research Gaps and Future Directions in GLP-1, Cancer Studies Most clinical evidence pertains to cancer incidence rather than progression, and the review calls for additional trials specifically in patients undergoing cancer treatment or in remission
Genetic polymorphisms affecting GLP-1 and GIP receptor expression, signaling pathways, or drug metabolism may reduce treatment efficacy in certain populations, though specific genetic markers have not yet been definitively identified for clinical use
Questions to ask any provider offering oral tirzepatide If a healthcare provider offers oral tirzepatide, ask these questions: What is the source of the tirzepatide used in this product
JAMA, 327(6), 534
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