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When the SNACsemaglutide complex reaches the gastric epithelium, the lipophilic SNAC enters the cell membrane, which affects its fluidity, leading to rapid transcellular absorption of semaglutide [14, 28]

GLP-1 therapy is ideal for adults with a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related health condition, who have struggled with other weight loss methods

Alcohol and GLP-1 monitoring: Many people starting GLP-1 medications already have some degree of MASLD

Due to these concerns, the FDA advises against using Mounjaro while pregnant unless the benefits outweigh potential risks

However, its weight-loss properties have sparked interest in the treatment of obesity as well