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Roughly 25-40% of total weight lost on GLP-1-class drugs is lean mass , and retatrutide's fat-to-lean ratio in trials is comparable to semaglutide and tirzepatide most of what you lose is fat
Many patients choose to receive B12 / MIC injections once weekly to help maintain consistent metabolic, energy, and wellness support
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Pfeffer AO, Samson HH (1988)
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