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In the NBC (nucleotide-binding cleft) mutant (233255), a region equivalent to that in the nucleotide-binding cleft of -actin was deleted
septic arthritis
3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide
To sustain this workload, heart tissue contains the highest concentration of mitochondria (cellular energy factories) of any muscle
The reaction rate approximately doubles for every 10C increase
