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If HbA1c remains above target after 12 weeks at 1 mg, escalate to 2 mg
It is part of what makes retatrutide unique compared to older molecules, as its half-life supports extended intervals without the need for daily administration
Those working with the 20mg vial may prefer 4ml to maintain the same 5mg/ml concentration
[10] [12] Importantly, they also act on appetite-regulating centres in the hypothalamus, leading to reduced hunger and increased satiety
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