In its own right, betaine has been shown to improve vascular risk factors and enhance athletic performance in addition to its role in methylation for NAD+ production and other metabolic processes.11 19 You can find high doses of TMG in products by Innerbody Labs, Prohealth Longevity, and Thorne
It improves joint mobility and enhances recovery from injuries by increasing blood flow to tendons and ligaments, supporting efficient tissue repair
You can use it with other products to take care of your skin
Increased levels of indoleacrylic acid (IDA) in the gut microbiota were reported to contribute to its accumulation in the retina, ultimately provoking ferroptosis of RGCs via the AhR/ALDH1A3/FSP1 axis (103)
Between now and those two dates, expect the agency to continue updating the 503A bulks reference document as nominations come in, get withdrawn, get clarified, and shift between categories