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Heres a highly simplified explanation of this pathway: 1
Arioglu, E
While BPC-157 circulates systemically regardless of administration route, local injection creates a concentration gradient favoring the target area
The pain receptors in the brain also seem to be affected by fibromyalgia, causing the brain to be overly sensitive to sensations of pain and overreact
The agency specifically noted that some patients were told by prescribers or telehealth platforms that topical application carried no risk of systemic side effects
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