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It is not recommended during pregnancy or breastfeeding

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Kohner EM, Henkind P (1970) Correlation of fluorescein angiogram and retinal digest in diabetic retinopathy

As a consequence, there is a massive secretion of water, provoking severe diarrhea ( Absorption of Calcium Intestinal Ca 2+ absorption is a critical physiological process for maintaining Ca 2+ homeostasis in the entire human body and involves both the transcellular and paracellular pathways