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It is a conjugate acid of a prostaglandin E1(1-)
Violante, F.V
This type of pain is often described as an intense burning sensation
But there's another number that deserves just as much attention: your estradiol, or E2
Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice
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