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The Massachusetts General Hospital published guidance emphasizing that the most effective strategy for preserving lean body mass during GLP-1 therapy involves combining a high-protein diet with consistent resistance exercise
It binds to copper, an essential mineral for healthy tissue, and helps increase collagen and elastin production, improve blood flow, and protect cells from damage
Kang and Tang, 2017) through pathways other than p62-Keap1-Nrf2
Together, they support: More consistent growth hormone activity Improved fat reduction Better muscle preservation Enhanced recovery Stronger metabolic support Many providers recommend combination therapy when patients want broad improvements across body composition, performance, and aging support