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Methylmalonic acid, if not properly handled by B 12 , remains in the myelin sheath, causing fragility

10.3390/metabo12010004 6 ChenC.XieT.ZhangY.WangY.YuF.LinL.et al (2023)

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In brief, the synovial tissues were collected, washed with PBS, chopped with scissors, and soaked in PBS mix with type I collagenase (4 mg/mL) in cell culture incubators for 3 h