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C32 and C88 in PfGrx) could not only form an intramolecular disulfide during catalysis or affect the reactivity of the active-site thiolate but also function as a resolving cysteine for trapped Grx(SSR) species (Fig

Loss of goblet cells and Paneth cells are early events in intestinal inflammation (9, 13) and have been associated with impaired metabolic fitness of IECs (9, 14)