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Studies suggest a role for brain-derived GLP-1 in the control of eating and reward (80, 81), but there is no evidence that peripherally administered GLP-1RAs can directly access GLP-1Rs in these regions, as demonstrated by the lack of fluorescently labeled semaglutide in these brain nuclei
The same active ingredient in Ozempic (semaglutide) is now licensed specifically for weight management under the brand name Wegovy at a higher dose
Nayan Patel, to discuss Glutathione
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doi: 10.1016/S2213-8587(24)00271-7
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