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But it can cause deep emotional wounds that are slow to heal

Confluence measurements of human NCI-H1299 cells NCI-H1299 cells were seeded on transparent 12-well plates (Corning Costar) and continuously treated with the indicated compounds

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Biochemically, due to intracellular GSH deprivation and GPX4 deactivation, lipid peroxides derived from Fe2+-catalyzed Fenton reaction fail to be eliminated through the GPX4-mediated reduction reaction, producing abundant reactive oxygen species (ROS), which facilitates ferroptosis (Stockwell et al., 2017