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To maximize the benefits of GLP-1s, it is recommended that you follow a healthy diet and engage in regular physical activity alongside your medication regiment
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These metabolic effects of tirzepatide on the liver are currently further investigated in another study (phase II trial) assessing the efficacy and safety of tirzepatide in patients with nonalcoholic steatohepatitis (SYNERGY-NASH, clinical trial registration number NCT04166773) (80)
Typical 12-month results include 10 to 15% body weight loss (20 to 35 pounds for a 200-pound person), 2 to 4 inch waist circumference reduction, noticeable improvement in body composition especially with exercise, and significant improvement in metabolic markers if they were elevated
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