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Selenophosphate synthetase 2 is the selenoenzyme that catalyzes the ATP-dependent synthesis of selenophosphate from hydrogen selenide ( Figure 4 ) (5)

10.1128/IAI.72.1.408-413.2004 Mishra S, Imlay J: Why do bacteria use so many enzymes to scavenge hydrogen peroxide

The FDA website hosts prescribing information for Mounjaro (tirzepatide for diabetes) and Zepbound (tirzepatide for weight loss)

This means that thyroid cells need to maintain their level of oxidative stress within a certain range, rather than uniformly attempting to lower it by producing more anti-ROS enzymes and molecules like glutathione