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At the same time different neural cells perform distinct functions: more that five hundred million years of nervous system evolution segregated neural cells into electrically excitable neurones responsible for input/output information transfer and information processing and electrically non-excitable neuroglia, 2,3,4 which provide homoeostatic support and defence of the nervous tissue

The arrangement of the transmembrane helices reveals hallmarks of an active conformation similar to that observed in class A receptors

Taken after the metabolic window closes, it offers minimal benefit, which is why timing and formulation determine outcomes

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