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In normal digestion, the contents in the stomach are emptied into the duodenum in a controlled manner, breaking down larger food particles into smaller portions for easier digestion

Co-secreted with GLP-1, their combined administration produces stronger anorectic and metabolic benefits than either alone (107)

While these drugs may lead to long-term cost savings by reducing obesity-related health complications, the immediate financial impact is a major concern

Temporary dose reduction often allows symptom resolution while maintaining therapeutic benefit

This suggests the possibility of emergence of resistance to arginine depletion, probably by re-expression of ASS1 or autophagy