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Negative symptoms include reduced tactile and thermal sensations, numbness, hypoesthesia, or anaesthesia [12]

Table A : GLP-1RAs versus other glucose-lowering agents: key specific features that impact treatment choice Given that there are few head-to-head studies comparing glucose-lowering effects between different drug classes, and the difficulty involved in performing cross-study comparisons due to different patient characteristics and baseline HbA 1c levels, there is widespread consensus that GLP-1RAs are more efficacious at lowering blood glucose than either DPP-IVs or SGLT-2 inhibitors

But back to the Ozempic

Their success in managing both diabetes and obesity has been revolutionary, with GLP-1 RAs demonstrating substantially improved efficacy over last-generation interventions

This is one more reason these decisions belong with a healthcare professional and outside the scope of DIY use