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Of note, over the last years, an array of unimolecular GLP1-based poly-agonists, with different mechanisms of action, have been developed and experimentally validated for the treatment of metabolic syndrome, holding superior efficacy relative to conventional GLP1-RA 33,34,35
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The companys portfolio centers on delivering functional copies of disease-relevant genes directly into the central nervous system to elevate deficient proteins and, in theory, slow or halt disease progression
A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study
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