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Service FJ, Molnar GD, Rosevear JW, Ackerman E, Gatewood LC, Taylor WF

With these methods, assuming no difference in cardiovascular risk between tirzepatide and comparators, it was determined that 133 participants with MACE-4 would provide 90% power to exclude the upper limit of the 95% CI of 1.8 at two-sided alpha = 0.05

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