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A disturbance in the balance of free radicals and reactive oxygen and nitrogen species can lead to cellular and organ damage from oxidative destruction of lipids, proteins, DNA, and RNA
pneumoniae , which lacks catalase and common regulators of peroxide stress resistance, can by itself generate and release millimolar levels of H 2 O 2 as a virulence factor ( 2 O 2 levels are high enough to kill or inhibit the growth of other common inhabitants of the respiratory tract, such as Haemophilus influenzae and Staphylococcus aureus , presumably as an evolutionary strategy to promote S
Additionally, Zhang et al
PER1 has been suggested to influence cancer progression once cancer has been established
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